Source: SpaceTelescope

V1 in M31.
Image credit: NASA, ESA and the Hubble Heritage Team (STScI/AURA)
Though the Universe is filled with billions upon billions of stars, the NASA/ESA Hubble Space Telescope has been trained on a single variable star that in 1923 altered the course of modern astronomy. And, at least one famous astronomer of the time lamented that the discovery had shattered his world view.
The star goes by the inauspicious name of Hubble variable number one, or V1, and resides two million light-years away in the outer regions of the neighbouring Andromeda galaxy, or M31. V1 is a special class of pulsating star called a Cepheid variable that can be used to make reliable measurements of large cosmic distances.
The star helped Edwin Hubble show that Andromeda lies beyond our galaxy. Prior to the discovery of V1 many astronomers, including Harlow Shapley, thought spiral nebulae, such as Andromeda, were part of our Milky Way galaxy. Others weren't so sure. In fact, Shapley and Heber Curtis held a public debate in 1920 over the nature of these nebulae. But it took Edwin Hubble's discovery just a few years later to settle the debate.
Hubble sent a letter, along with a light curve of V1, to Shapley telling him of his discovery. After reading the note, Shapley reportedly told a colleague, "Here is the letter that destroyed my Universe." The Universe became a much bigger place after Edwin Hubble's discovery.
In commemoration of this landmark observation, astronomers with the Space Telescope Science Institute's Hubble Heritage Project partnered with the American Association of Variable Star Observers (AAVSO) to study the star. AAVSO observers followed V1 for six months, producing a plot, or light curve, of the rhythmic rise and fall of the star's light. Based on this data, the Hubble Heritage team scheduled Hubble telescope time to capture Wide Field Camera 3 images of the star at its dimmest and brightest light levels.
These observations were presented on 23 May at the meeting of the American Astronomical Society in Boston.